How to determine the optimal flip angle for each patient in hepatobiliary-phase easily and quickly during Gd-EOB- DTPA-MRI examination? Recommends using imaging findings of cirrhotic liver as the indicator
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[Basic evaluation of the optimal flip angle for hepatocyte phase with gadolinium ethoxybenzyl diethylenetriamine pantaacetic acid: selection of the optimal flip angle by the imaging findings].
Gadolinium ethoxybenzyl diethylenetriamine pantaacetic acid (Gd-EOB-DTPA) is incorporated into liver cells, and liver parenchyma show hyperintensity due to the T1 shortening effect. The T1 value of liver parenchyma in the hepatocyte phase changes from the pre-contrast phase. However, in patients with liver dysfunction, the difference of T1 value is generally small. In examination of hepatic dis...
متن کاملEvaluation of hypointense liver lesions during hepatobiliary phase MR imaging in normal and cirrhotic livers: is increasing flip angle reliable?
Gd-EOB-DTPA is a newly developed liver specific magnetic resonance contrast agent, which is widely used for focal liver lesion (FLL) detection and liver function evaluation. However, it has been demonstrated that hepatocytes uptake of Gd-EOB-DTPA obviously decreased in cirrhotic liver, and cirrhotic liver parenchyma may show reduced enhancement in hepatobiliary phase, which would result in decr...
متن کاملFlip angle Optimization with Hepatobiliary Contrast Agents at 3T
INTRODUCTION: To date, two FDA-approved Gadolinium-based contrast agents Gd-EOBDTPA (Gadoxetate, Eovist, Bayer Pharmaceuticals, Wayne, NJ), and Gd-BOPTA (Gadobenate, Bracco Diagnostics, Princeton, NJ) are available for hepatobiliary imaging. The pharmacokinetics of these agents are different, with approximately 4-5% hepatic uptake with Gd-BOPTA at 1-2 hours, and 50% uptake of Gd-EOB-DTPA at app...
متن کاملGadolinium ethoxybenzyl diethylenetriamine pentaacetic Acid-enhanced magnetic resonance imaging findings of borderline lesions at high risk for progression to hypervascular classic hepatocellular carcinoma.
OBJECTIVES The objectives of the study were to assess the imaging features of hypovascular borderline lesions containing hypervascular foci on gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) and to evaluate the ability of Gd-EOB-DTPA-enhanced MRI to diagnose high-risk borderline lesions possibly consistent with early hepatocell...
متن کاملMultiple FNH-Like Lesions in a Patient with Chronic Budd-Chiari Syndrome: Gd-EOB-Enhanced MRI and BR1 CEUS Findings
A-26-year old female patient with chronic Budd-Chiari syndrome due to different underlying blood disorders applied for a two-year followup of the liver with Gadolinium-ethoxybenzyl-diethylenetriaminepentaacetic-acid-(Gd-EOB-DTPA-) enhanced MRI. The liver function tests were raised. Besides showing a progressive hepatosplenomegaly and a cirrhotic liver alteration, the MRI revealed multiple new n...
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تاریخ انتشار 2014